Bacillus coagulans, a revolutionary new friendly bacteria naturally occurring in the intestine. It is a spore-forming bacteria that make it the choice of probiotic with enormous clinical applications. B. coagulans is a notable exemption which, due to its sporulated form, lives without special handling and proliferates in the gastrointestinal environment rapidly. Due to its spore forming environment, B. coagulans is unaffected to most chemical and physical conditions e.g. Temperature, harsh and persists manufacturing, transport and storage with no loss of viable count. It does not require refrigeration condition and is stable at room temperature. B. coagulans has gained wide application as a biotherapeutic agent in treatment of various chronic diseases including gastrointestinal (GI) to non-GI tract infections. Through the keen references, on B. coagulans we have focused on safety, microbiological background, pharmacokinetics and clinical indications of B. coagulans.
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